The Winn Feline Foundation recently announced the award of six grants funded in partnership with the George Sydney and Phyllis Redman Miller trust in 2010. Totaling $103,185, the grants helped fund studies on anesthesia and feline hypertrophic cardiomyopathy, pain management, asthma, liver disease, herpesvirus, and chronic renal failure.
The first study aims to help veterinarians make the most appropriate drug choice to treat anesthetic-induced hypotension in cats with hypertrophic cardiomyopathy, the most common cardiac disease of clinical significance in cats.
The second study investigates the transmucosal (entering through a mucous membrane) absorption and analgesic (pain-relieving) efficacy of opioids in cats.
Seeking to understand the pharmacokinetics (what the body does to a drug) of the drug bosentan, the third study evaluates the drug as a future therapeutic choice for cats with asthma.
The fourth study investigates the role of bacterial cell wall components, cytokine signaling, and myofibroblastic fibrosis in feline nonsuppurative cholangitis-cholangiohepatitis syndrome, the most common inflammatory liver disease affecting cats, as an aid to improving diagnostic categorization and treatment methods.
Addressing the use of RNA interference as a potential therapeutic for feline herpesvirus, the fifth study evaluates topical delivery methods and seeks to identify the best carrier agent to deliver this therapeutic modality into feline corneal cells in vivo.
Lastly, the sixth study will determine if vitamin E supplementation will benefit cats with chronic renal failure.
For more information, visit the Winn Feline Foundation.