Incurin (estriol) is intended for the control of estrogen-responsive urinary incontinence in spayed female dogs.
Hormone-responsive incontinence can occur months to years after a dog is spayed and is a common problem in middle-aged and elderly spayed female dogs. Dogs affected can urinate normally and show no signs of ill health, but leak urine while resting.
Incurin is manufactured by Merck Animal Health of Summit, N.J. A natural estrogen hormone, it increases the resting muscle tone of the urethra. The drug can also be used to treat female dogs affected by urinary incontinence due to estrogen depletion.
In a study of 226 spayed female dogs, a greater percentage of dogs treated with Incurin improved compared to dogs treated with placebo. Incurin was shown to be effective for the control of estrogen-responsive urinary incontinence in spayed female dogs 1 year and older.
Loss of appetite, vomiting, excessive water drinking and swollen vulva are some of the drug’s side effects. The drug is not yet available through veterinarians, but is expected to be released in the future. Ask your veterinarian for more information and to discuss potential options for treating your dog.